The federal government is phasing out off-brand copies of two blockbuster drugs used to treat obesity and diabetes.

The NBA’s All-Star Game is going to be an All-Star tournament this season, with the league announcing that it has finalized plans to use a different format for the upcoming midseason showcase in San Francisco.

Indiana officials are preparing to execute the state’s first death row inmate in 15 years.

College football’s conference shakeup left concerns about two super conferences dominating the playoff field.

Oregon and Penn State piled up seven touchdowns, 537 yards, 28 first downs and 55 points in the Big Ten title game.

Undefeated Oregon pulled off the expected and grabbed the top spot in the College Football Playoff.

Eli Lilly is spending another $3 billion to bulk up manufacturing as the drugmaker seeks to stoke production of some blockbuster drugs and future products.

Anthem Blue Cross Blue Shield says it won't tie payments to the length of time a patient went under anesthesia.

WNBA star Caitlin Clark has joined Cincinnati’s bid for an expansion National Women’s Soccer League team.

Roger Penske has added the most prestigious street race in North America to his portfolio with the purchase of the Grand Prix of Long Beach.

Caitlin Clark has one goal when she plays in an LPGA pro-am.

The NBA is considering changing the format for the All-Star Game that will be played in San Francisco later this season, Commissioner Adam Silver said.

Eli Lilly is dialing back its 2024 forecast after underwhelming Wall Street with third-quarter earnings and sales from two key drugs that missed expectations.

The Washington Mystics are parting ways with coach Eric Thibault and general manager Mike Thibault.

Elevance Health surprised Wall Street with a rare, late-year guidance cut Thursday after a jump in Medicaid costs marred its third quarter.

The cost of a Mega Millions lottery ticket will soon more than double, but officials said they’re confident players won’t mind paying more after changes that will lead to larger prizes and more frequent winners.

Paralyzed in a racing accident nearly 25 years ago, Sam Schmidt has spent much of the last quarter century trying to prove to others that there is a way to have a meaningful life with a traumatic spinal cord injury.

Joe Flacco threw two touchdown passes in relief of the injured Anthony Richardson, and the Indianapolis Colts came up with a stop in the final minute to beat the Pittsburgh Steelers 27-24.

Caitlin Clark and the Indiana Fever have clinched the sixth seed in the WNBA playoffs.

It was another record-breaking night for Indiana Fever star Caitlin Clark.

A’ja Wilson became the WNBA’s single-season scoring leader and finished with 27 points and 12 rebounds to help the Las Vegas Aces beat the Indiana Fever 86-75 on Wednesday night for their 14th straight win in the series.

A’ja Wilson broke the WNBA single season scoring record just before the first half of the Las Vegas Aces’ game against the Indiana Fever on Wednesday night.

Napheesa Collier scored nine of her 26 points in the third quarter, Bridget Carleton made three 3-pointers in the final four minutes and the Minnesota Lynx overcame a 25-point night by Caitlin Clark to snap Indiana’s five-game winning streak with a 99-88 win over the Fever.

Caitlin Clark became the fastest player in WNBA history to reach 100 3-pointers in a season and finished with 24 points, 10 rebounds and 10 assists for her second career triple-double as the playoff-bound Indiana Fever beat the Los Angeles Sparks 93-86.

Caitlin Clark and the Indiana Fever clinched a playoff berth without playing.

Kelsey Mitchell scored 23 points, Caitlin Clark had 19 points, five rebounds and five assists, and the Indiana Fever beat the Connecticut Sun 84-80 to snap an 11-game losing streak in the series.

Michigan has received the final version of a notice of allegations from the NCAA related to an investigation into an in-person scouting and sign-stealing operation being run by a football staffer.

Kelsey Mitchell scored 27 points, Caitlin Clark added 23 points and nine assists, and Lexie Hull scored 12 of her career-high 22 points in the fourth quarter Sunday to help the Indiana Fever beat the Seattle Storm 92-75.

Caitlin Clark started fast and finished with 29 points and 10 assists while Kelsey Mitchell scored 28 points to help the Indiana Fever fend off a furious second-half rally from the Phoenix Mercury for a critical 98-89 victory on Friday night.

Indianapolis will host the 2025 WNBA All-Star Game at Gainbridge Fieldhouse next July.

Indiana’s attorney general has dropped a lawsuit accusing the state’s largest hospital system of violating patient privacy laws when a doctor told a newspaper that a 10-year-old Ohio girl had traveled to Indiana for an abortion.

The College Football Playoff expands to from four to 12 teams this season, a massive change that will profoundly impact the sport and how success is defined.

Major League Baseball is coming to Bristol Motor Speedway with the Braves and the Reds taking part in the Speedway Classic in August 2025.

Eli Lilly blew past second-quarter expectations with the diabetes treatment Mounjaro and its weight loss counterpart Zepbound funneling more than $4 billion in sales to the drugmaker.

In another disappointment for the American swim team, Simone Manuel has been eliminated in the preliminaries of the 50-meter freestyle.

Vice President Kamala Harris has crashed the season finale of “RuPaul’s Drag Race All Stars,” urging Americans to vote in an appearance taped before President Joe Biden dropped his reelection bid.

Democratic National Convention delegates can make Vice President Kamala Harris their presidential nominee — and even approve her yet-to be-named running mate — in online voting beginning next week.

Kamala Harris is set to hold a campaign rally in Indianapolis at 12 p.m. today.

Ohio State coach Ryan Day sounds confident and comfortable discussing this year’s football team.

Kyle Larson made a late charge through the field, managed to get his car refired after a red flag and won the final two restart battles Sunday before coasting to his first Brickyard 400 victory under caution.

Caitlin Clark made her first appearance at Indianapolis Motor Speedway — on Josh Berry’s No. 4 Ford.

The door to Clark actually being in Paris has opened, albeit slightly.

Kyle Larson's double attempt in May drew the attention of racing fans everywhere.

The U.S. has won more gold medals (257) than any other nation has won total medals in Olympic swimming.

A pipe organ that provided the live music for silent movies in an ornate Detroit theater nearly a century ago is set to become the centerpiece of a performing arts center on a New York college campus.

Kelsey Mitchell scored 28 points, Caitlin Clark had 20 points and 13 assists for her fifth straight double-double and the Indiana Fever beat the short-handed Phoenix Mercury 95-86.

Caitlin Clark leads Angel Reese in the race for WNBA Rookie of the Year honors at the midpoint of the season, according to a national panel of voters who also rank the AP Power Poll each week.

Caitlin Clark posted the first triple-double by a rookie in WNBA history to rally Indiana to an 83-78 victory over New York on Saturday at Gainbridge Fieldhouse, snapping the Fever’s nine-game losing streak to the Liberty.

Police say Vikings rookie cornerback Khyree Jackson has been killed in a car crash in Maryland.

The Atlanta Hawks are finalizing talks to trade high-scoring Dejounte Murray to the New Orleans Pelicans for a package expected to include two first-round draft picks, according to people with knowledge of the discussions.

A small Texas university has gone to court to object to the $2.77 billion settlement proposal that would erase a set of antitrust claims against the NCAA and the nation’s largest conferences and clear the way for schools to begin steering millions of dollars directly to athletes as soon as fall 2025.

A’ja Wilson leads Caitlin Clark by just over 1,000 votes in early fan voting for the WNBA All-Star Game.

The 2028 Los Angeles Olympics announced changes to its venue plan that it says will create an estimated $156 million in combined savings and revenue increases.

Four of America’s biggest swimming stars have doubled up at the U.S. Olympic swimming trials.

Former Vice President Mike Pence’s foundation is launching a $10 million campaign to preserve the Trump-era tax cuts.

A blistering heat wave stretching from the Midwest to the tip of Maine is leaving millions of people sweltering through the Juneteenth holiday.

Regan Smith has set a world record in the women's 100-meter backstroke at the U.S. Olympic swimming trials in Indianapolis.

Gretchen Walsh followed up a world record in the 100-meter butterfly with something that felt just as good.

Gretchen Walsh set a world record in the women’s 100-meter butterfly, posting a time of 55.18 seconds in a semifinal heat at the U.S. Olympic swimming trials.

Katie Ledecky is off to a rousing start at the U.S. Olympic swimming trials.

Preliminaries in events will take place from 11 a.m. to 2 p.m. each day, with finals being held from 8 p.m. to 11 p.m. to determine which swimmers will represent Team USA in Paris.

Delegates at the Southern Baptist Convention’s annual meeting have narrowly rejected a proposal to enshrine a ban on churches with women pastors in the denomination’s constitution.

Waffle House is increasing pay for its U.S. workers after a push from labor advocates.

The lead singer of the Four Tops says a Detroit-area hospital restrained him and ordered a psychological exam after refusing to believe that he was part of the Motown music group.

Caitlin Clark hopes to play for the U.S. Olympic team one day.

An Ohio-based Christian nonprofit that organizes off-campus Bible classes for public school students has taken off in Indiana since the state passed legislation forcing school districts to comply.

Caitlin Clark was asked before her game at Washington whether she thinks Chennedy Carter owes her a public apology.

Agustín Canapino is taking a leave of absence from IndyCar racing after he disputed Theo Pourchaire's claim that Argentine fans had issued death threats to the rival driver this week.

Indianapolis Colts quarterback Anthony Richardson played it safe on the final day of minicamp, resting his sore right shoulder.

Caitlin Clark finally got the break she needed this week.

The Dallas Mavericks and Boston Celtics prepare to tip off the NBA Finals and the four biggest names in the series are looking at this moment through different lenses.

NASCAR has granted Kyle Larson the waiver he needs to remain eligible to compete in this year’s playoffs despite missing the Coca-Cola 600 because he instead ran the Indianapolis 500.

The WNBA has upgraded Chicago Sky guard Chennedy Carter’s foul against Indiana Fever guard Caitlin Clark to a flagrant-1 violation after reviewing the play.

Josef Newgarden continued a busy week Saturday with a third-place qualifying run in Detroit and a contract extension with Penske Racing.

Pato O’Ward had tears triggered following the Indianapolis 500 after pushing the No. 5 Honda to the limits only to come up just short, getting passed two corners from the finish by Josef Newgarden.

The NCAA and a coalition of states suing the organization have announced a proposed settlement of a lawsuit that would allow athletes to play immediately no matter how many times they transfer.

Front Row Motorsports has purchased a charter that will expand the NASCAR team to three cars in the Cup Series in 2025.

Kia Nurse scored 22 points and Aari McDonald added a season-high 21 to help the Los Angeles Sparks rally for a 88-82 victory over the Indiana Fever, handing Caitlin Clark her third straight home loss.

The Boston Celtics completed one quest Monday night by making it back to the NBA Finals.

Kyle Larson spent a year preparing to run the double.

Marcus Ericsson, the 2022 Indianapolis 500 champion and 2023 runner-up, was knocked out of Sunday's race before completing a lap as part of a three-car crash.

Jrue Holiday overcame an illness to convert the go-ahead three-point play with 38 seconds left, then make the game-saving steal to help the Boston Celtics rally from an 18-point deficit to beat the Indiana Pacers 114-111 on Saturday night for a 3-0 lead in the Eastern Conference finals.

Pato O'Ward has become one of IndyCar's biggest stars not just for the way he drives on the track but the way he carries himself away from it.

Eli Lilly will spend more than $5 billion to expand an Indiana manufacturing site and eventually make more doses of its hot-selling weight-loss and diabetes treatments, Zepbound and Mounjaro.

The Las Vegas Raiders are rewarding star pass rusher Maxx Crosby with a $6 million raise this season and another $1.2 million next year.

Caitlin Clark intends to play Wednesday night despite a stiff and sore left ankle when the Indiana Fever open a road trip in Seattle against the Storm.

The Seattle Storm are a work in progress with Nneka Ogwumike and Skylar Diggins-Smith trying to get into a groove with Jewell Loyd.

Kyle Larson has been trying to soak up the Indianapolis 500 experience before making his debut on Sunday.

Caitlin Clark has signed a multiyear deal with Wilson Sporting Goods for a signature basketball line.

Tyasha Harris scored 13 of Connecticut’s final 18 points Monday night, including two free throws with 10.9 seconds left, and the Sun kept the Indiana Fever and rookie Caitlin Clark winless through four games with an 88-84 victory Monday night.

Caitlin Clark returned for the start of the second half of the Indiana Fever's game against the Connecticut Sun after what appeared to be an injured lower left leg in the first half Monday night.

Colton Herta and Andretti Global showed some speed in the penultimate Indianapolis 500 practice session as cars reverted to race setups after qualifying.

OG Anunoby and Josh Hart are in the New York Knicks’ starting lineup for Game 7 of the Eastern Conference semifinals against the Indiana Pacers.

Starting forwards Josh Hart and OG Anunoby are both listed as questionable to play for the New York Knicks on Sunday in Game 7 of their Eastern Conference semifinal series against the Indiana Pacers.

Team Penske swept three of the top four spots in Saturday qualifying for the Indianapolis 500 to give the team under so much scrutiny a solid shot at winning the pole for “The Greatest Spectacle in Racing.”.

There are two Game 7s in the NBA on Sunday.

Pascal Siakam scored 25 points and Myles Turner added 17 points to help the Indiana Pacers turned the tables on New York with a 116-103 victory to even the Eastern Conference semifinal at 3-3.

All of the attention ahead of qualifying for the Indianapolis 500 is squarely on Team Penske.

Stay tuned for what likely be a controversial decision no matter what it ends up being.

Breanna Stewart ruined Caitlin Clark's regular season home debut by scoring 31 points and leading the New York Liberty to a 102-66 victory at Indiana.