Pence, whose future political aspirations could hinge on November, has campaigned aggressively for the president.
Pence has helped steer the White House response to the coronavirus, leading a task force and frequently working with the nations governors.
The GOP convention has mentioned the virus far less than Democrats did last week, but Pence could throw it back into focus if he speaks about the work hes led.
Conway, whose husband has become an outspoken Trump critic, says she is stepping away to spend more time with her family.
Clarence Henderson, a civil rights activist from the 1960s, is expected to speak on the true meaning of peaceful protest."