The Jacksonville Jaguars have ended their 20-game losing streak.

Sam Darnold threw for 305 yards and two touchdowns, and the Carolina defense turned in another strong performance in a 26-7 win over the New Orleans Saints on Sunday.

San Francisco 49ers running back Jeff Wilson (30) celebrates his touchdown against the Arizona Cardinals with quarterback C.J. Beathard threw three touchdown passes, Jeff Wilson ran for 183 yards, and the San Francisco 49ers dealt a brutal blow to the Arizona Cardinals' playoff hopes by defeating them 20-12 on Saturday. If the Chicago Bears win their final two games, they will reach the playoffs because of a tiebreaker over the Cardinals. The 49ers (6-9) pulled ahead 14-6 in the third quarter on Beathard’s 9-yard touchdown pass to fullback Kyle Juszczyk. Cardinals: LB Haason Reddick (hamstring) left the game in the first quarter, but returned early in the second quarter.

The Patriots, who can extend their NFL record to 11 consecutive playoff berths with a win, will also be missing a key offensive cog. ___KANSAS CITY-NEW ENGLANDChiefs: RB Damien Williams, CB Rashad Fenton, CB Morris Claiborne, OL Jackson Barton, OL Nick Allegretti, TE Deon Yelder, QB Chad Henne. Patriots: C Ted Karras, DL Byron Cowart, CB Joejuan Williams, QB Cody Kessler, OL Korey Cunningham, TE Ryan Izzo, RB Damien Harris. Bills: RB T.J. Yeldon, S Dean Marlowe, OG Ike Boettger, RT Ty Nsekhe, WR Duke Williams, TE Tommy Sweeney, DT Vincent Taylor. Packers: WR Ryan Grant, CB Kevin King, RB Dexter Williams, CB Tony Brown, CB Ka'dar Hollman, G/T Adam Pankey, T Yosh Nijman.